Complement receptor is an inhibitor of the complement cascade.
نویسندگان
چکیده
منابع مشابه
Complement receptor is an inhibitor of the complement cascade
A glycoprotein from the membrane of human erythrocytes has been identified as a receptor for C3b (CR1). It promotes the dissociation of the alternative pathway C3 convertase C3b,Bb and the cleavage of C3b by C3b/C4b inactivator. We find that CR1 also inactivates the C3 and C5 convertases of the classical pathway. CR1 inhibits the consumption of C3 by C3 convertase EAC142 and enhances the decay ...
متن کاملSOLVING FUZZY LINEAR SYSTEMS BY USING THE SCHUR COMPLEMENT WHEN COEFFICIENT MATRIX IS AN M-MATRIX
This paper analyzes a linear system of equations when the righthandside is a fuzzy vector and the coefficient matrix is a crisp M-matrix. Thefuzzy linear system (FLS) is converted to the equivalent crisp system withcoefficient matrix of dimension 2n × 2n. However, solving this crisp system isdifficult for large n because of dimensionality problems . It is shown that thisdifficulty may be avoide...
متن کاملcer and the Complement Cascade
ownload pite significant research on the role of inflammation and immunosurveillance in the immunologic nvironment of tumors, little attention has been given to the oncogenic capabilities of the complement e. The recent finding that complement may contribute to tumor growth suggests an insidious relationship n complement and cancer, especially in light of evidence that complement facilitates ce...
متن کاملOsteoarthritis and the Complement Cascade
Accumulating evidence demonstrates that complement activation is involved in the pathogenesis of osteoarthritis (OA). However, the intimate complement regulation and cross talk with other signaling pathways in joint-associated tissues remain incompletely understood. Recent insights are summarized and discussed here, to put together a more comprehensive picture of complement involvement in OA pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1981
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.153.5.1138